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 The leading web portal for pharmacy resources, news, education and careers October 20, 2018
Pharmacy Choice - Pharmaceutical News - New Hydrocephalus Findings from Oslo University Hospital Described (Cerebrospinal fluid disturbances after 381 consecutive craniotomies for... - October 20, 2018

Pharmacy News Article

 1/5/15 - New Hydrocephalus Findings from Oslo University Hospital Described (Cerebrospinal fluid disturbances after 381 consecutive craniotomies for...

New Hydrocephalus Findings from Oslo University Hospital Described (Cerebrospinal fluid disturbances after 381 consecutive craniotomies for intracranial tumors in pediatric patients)

By a News Reporter-Staff News Editor at Pain & Central Nervous System Week Researchers detail new data in Nervous System Diseases and Conditions. According to news reporting originating from Oslo, Norway, by NewsRx correspondents, research stated, "The aim of this study was to investigate the incidence of CSF disturbances before and after intracranial surgery for pediatric brain tumors in a large, contemporary, single-institution consecutive series. All pediatric patients (those < 18 years old), from a well-defined population of 3.0 million inhabitants, who underwent craniotomies for intracranial tumors at Oslo University Hospital in Rikshospitalet between 2000 and 2010 were included."

Our news editors obtained a quote from the research from Oslo University Hospital, "The patients were identified from the authors' prospectively collected database. A thorough review of all medical charts was performed to validate all the database data. Included in the study were 381 consecutive craniotomies, performed on 302 patients (50.1% male, 49.9% female). The mean age of the patients in the study was 8.63 years (range 0-17.98 years). The follow-up rate was 100%. Primary craniotomies were performed in 282 cases (74%), while 99 cases (26%) were secondary craniotomies. Tumors were located supratentorially in 249 cases (65.3%), in the posterior fossa in 105 (27.6%), and in the brainstem/diencephalon in 27 (7.1%). The surgical approach was supratentorial in 260 cases (68.2%) and infratentorial in 121 (31.8%). Preoperative hydrocephalus was found in 124 cases (32.5%), and 71(86.6%) of 82 achieved complete cure with tumor resection only. New-onset postoperative hydrocephalus was observed in 9 (3.5%) of 257 cases. The rate of postoperative CSF leaks was 6.3%. Preoperative hydrocephalus was found in 32.5% of pediatric patients with brain tumors treated using craniotomies."

According to the news editors, the research concluded: "Tumor resection alone cured preoperative hydrocephalus in 86.6% of cases and the incidence of new-onset hydrocephalus after craniotomy was only 3.5%."

For more information on this research see: Cerebrospinal fluid disturbances after 381 consecutive craniotomies for intracranial tumors in pediatric patients. Journal of Neurosurgery-Pediatrics, 2014;14(6):604-614. Journal of Neurosurgery-Pediatrics can be contacted at: Amer Assoc Neurological Surgeons, 5550 Meadowbrook Drive, Rolling Meadows, IL 60008, USA (see also Nervous System Diseases and Conditions).

The news editors report that additional information may be obtained by contacting S.A.M. Hosainey, Oslo Univ Hosp, Dept. of Neurosurg, N-0027 Oslo, Norway. Additional authors for this research include B. Lassen, E. Helseth and T.R. Meling.

Keywords for this news article include: Oslo, Norway, Europe, Pediatrics, Hydrocephalus, Central Nervous System Diseases, Nervous System Diseases and Conditions

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2015, NewsRx LLC



(c) 2015 NewsRx LLC

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