Reports Outline Health and Medicine Study Findings from University of Sussex (Intravenous versus Subcutaneous Drug Administration. Which Do Patients Prefer? A Systematic Review)
By a News Reporter-Staff News Editor at Clinical Trials Week New research on Health and Medicine is the subject of a report. According to news reporting originating from Brighton, United Kingdom, by NewsRx correspondents, research stated, "Intravenous (IV) drug delivery is commonly used for its rapid administration and immediate drug effect. Most studies compare IV to subcutaneous (SC) delivery in terms of safety and efficacy, but little is known about what patients prefer."
Our news editors obtained a quote from the research from the University of Sussex, "A systematic review was conducted by searching seven electronic databases for articles published up to February 2014. Included studies were randomized controlled trials (RCTs) and/or crossover designs investigating patient preference for SC versus IV administration. The risk of bias in the RCTs was determined using the Cochrane Collaboration tool. Reviewers independently extracted data and assessed the risk of bias. Any discrepancies were resolved by consensus. The search identified 115 publications, but few (6/115) met the inclusion criteria. Patient populations and drugs investigated were diverse. Four of six studies demonstrated a clear patient preference for SC administration. Main factors associated with SC preference were time saving and the ability to have treatment at home. Only three studies used study-specific instruments to measure preference. Results suggest that patients prefer SC over IV delivery. Patient preference has clearly been neglected in clinical research, but it is important in medical decision making when choosing treatment methods as it has implications for adherence and quality of life. If the safety and efficacy of both administration routes are equivalent, then the most important factor should be patient preference as this will ensure optimal treatment adherence and ultimately improve patient experience or satisfaction."
According to the news editors, the research concluded: "Future drug efficacy and safety studies should include contemporaneous, actual patient preference where possible, utilizing appropriate measures."
For more information on this research see: Intravenous versus Subcutaneous Drug Administration. Which Do Patients Prefer? A Systematic Review. Patient-Patient Centered Outcomes Research, 2015;8(2):145-153. Patient-Patient Centered Outcomes Research can be contacted at: Adis Int Ltd, 5 The Warehouse Way, Northcote 0627, Auckland, New Zealand (see also Health and Medicine).
The news editors report that additional information may be obtained by contacting K.L. Stoner, University of Sussex, SHORE C, Brighton & Sussex Med Sch, Brighton BN1 9RX, E Sussex, United Kingdom. Additional authors for this research include H. Harder, L.J. Fallowfield and V.A. Jenkins.
Keywords for this news article include: Europe, Brighton, United Kingdom, Health and Medicine
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