Studies from Albert Einstein College of Medicine Add New Findings in the Area of Orthostatic Hypotension (Droxidopa for Symptomatic Neurogenic Hypotension)
By a News Reporter-Staff News Editor at Drug Week Researchers detail new data in Autonomic Nervous System Diseases and Conditions - Orthostatic Hypotension. According to news reporting from Bronx, New York, by NewsRx editors, the research stated, "Droxidopa is a first-in-class, orally available, synthetic amino acid precursor of norepinephrine that received accelerated Food and Drug Administration approval in February 2014 after Orphan Drug status for a debilitating condition known as symptomatic neurogenic orthostatic hypotension. Neurogenic disorders often lead to postural hypotension as a result of poor norepinephrine release from its storage sites."
The news correspondents obtained a quote from the research from the Albert Einstein College of Medicine, "Clinical data suggest increases in standing systolic blood pressure and improvements in many other markers for subjective relief in patients with symptomatic neurogenic hypotension who received droxidopa therapy over 1-2 weeks. Studies evaluating the sustained effects of droxidopa are ongoing. With minimal drug interactions (even with carbidopa use) or adverse effects, droxidopa therapy can be used safely in patients with a variety of neurologic conditions; however, more data are needed to determine its appropriate pharmacotherapeutic role."
According to the news reporters, the research concluded: "In all, droxidopa is a safe and effective medication for the treatment of orthostatic dizziness/lightheadedness, or the 'feeling that you are about to black out' in adult patients with symptomatic neurogenic orthostatic hypotension secondary to primary autonomic failure (Parkinson's disease, multiple system atrophy, and pure autonomic failure), dopamine beta-hydroxylase deficiency, and nondiabetic autonomic neuropathy."
For more information on this research see: Droxidopa for Symptomatic Neurogenic Hypotension. Cardiology in Review, 2017;25(5):241-246. Cardiology in Review can be contacted at: Lippincott Williams & Wilkins, Two Commerce Sq, 2001 Market St, Philadelphia, PA 19103, USA (see also Autonomic Nervous System Diseases and Conditions - Orthostatic Hypotension).
Our news journalists report that additional information may be obtained by contacting N. Ferguson-Myrthil, Albert Einstein College of Medicine, Weiler Hosp, Montefiore Med Center, Dept. of Pharm, Bronx, NY 10461, United States.
Keywords for this news article include: Bronx, New York, United States, North and Central America, Autonomic Nervous System Diseases and Conditions, Cardiovascular Diseases and Conditions, Orthostatic Hypotension, Droxidopa, Serine, Albert Einstein College of Medicine.
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