Data on Liver Function Reported by Researchers at Korea University Ansan Hospital (ALBI versus Child-Pugh grading systems for liver function in patients with hepatocellular carcinoma)
By a News Reporter-Staff News Editor at Cancer Weekly A new study on Liver Diseases and Conditions - Liver Function is now available. According to news reporting out of Ansan, South Korea, by NewsRx editors, research stated, "The prognostic performance of the albumin-bilirubin (ALBI) grade in hepatocellular carcinoma (HCC) as an objective method of assessing liver function was investigated. Data from 2099 patients with HCC in Korea were collected and analyzed retrospectively."
Our news journalists obtained a quote from the research from Korea University Ansan Hospital, "The discriminative performance of ALBI grade was compared with Child-Pugh (C-P) grade for different stages or treatments. The median follow up duration was 16.2 months (range: 1.0-124.9). The median survival times were 49.7 months for C-P grade A (65.8%), 12.4 months for C-P grade B (25.5%), and 4.2 months for C-P grade C (8.6%) (p <0.001). The median survival times were 84.2 months for ALBI grade 1 (32.8%), 25.5 months for ALBI grade 2 (53.5%), and 7.7 months for ALBI grade 3 (13.7%) (p <0.001). In early UICC stages, ALBI grade showed better discriminative performance than C-P grade. In curative treatments, ALBI grade also showed better discriminative performance than C-P grade (Harrell's C: 0.624 (C-P grade) vs 0.667 [ALBI grade])."
According to the news editors, the research concluded: "ALBI grade provided better prognostic performance in survival analysis and better distribution of the grades than C-P grade in HCC, suggesting that ALBI grade could be a good alternative grading system for liver function in patients with HCC."
For more information on this research see: ALBI versus Child-Pugh grading systems for liver function in patients with hepatocellular carcinoma. Journal of Surgical Oncology, 2018;():. (Wiley-Blackwell - www.wiley.com/; Journal of Surgical Oncology - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1096-9098)
Our news journalists report that additional information may be obtained by contacting S.K. Na, Division of Gastroenterology and Hepatology, Dept. of Internal Medicine, Korea University Ansan Hospital, Ansan, South Korea. Additional authors for this research include S.Y. Yim, S.J. Suh, Y.K. Jung, J.H. Kim, Y.S. Seo, H.J. Yim, J.E. Yeon, K.S. Byun and S.H Um (see also Liver Diseases and Conditions - Liver Function).
The direct object identifier (DOI) for that additional information is: https://doi.org/10.1002/jso.24992. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.
Keywords for this news article include: Asia, Ansan, Oncology, Carcinomas, Hepatology, South Korea, Liver Cancer, Liver Function, Gastroenterology, Health and Medicine, Liver Diseases and Conditions.
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