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 The leading web portal for pharmacy resources, news, education and careers March 23, 2019
Pharmacy Choice - Pharmaceutical News - Findings from Kitano Hospital Yields New Findings on Pancreatic Cancer (Clinical impact of margin status on survival and recurrence pattern after curative-intent surgery for pancreatic cancer) - March 23, 2019

Pharmacy News Article

 1/10/19 - Findings from Kitano Hospital Yields New Findings on Pancreatic Cancer (Clinical impact of margin status on survival and recurrence pattern after curative-intent surgery for pancreatic cancer)

By a News Reporter-Staff News Editor at Cancer Weekly Investigators discuss new findings in Oncology - Pancreatic Cancer. According to news reporting originating in Osaka, Japan, by NewsRx journalists, research stated, "The definition of R0 resection for invasive pancreatic ductal carcinoma (IPDC) is important. However, there are different definitions among several countries in the world."

The news reporters obtained a quote from the research from Kitano Hospital, "From 2001 to 2015, 100 consecutive patients with IPDC who underwent pancreatic resection in our hospital were enrolled. We compared survival and recurrence patterns between the R0 group and R1 group based on the UICC (Union for International Cancer Control) classification (current-R0 vs. current-R1) and based on our revised classification, which defines R0 as a surgical margin of >1 mm (revised-R0 vs. revised-R1). The 100 patients comprised 58 males and 42 females, and their median age was 70 [32-87]. There were 84 patients in the current-R0 group and 43 in the revised-R0 group. There was no difference in overall survival (OS) or recurrence-free survival (RFS) between the current-R0 group and current-R1 group. However, there was a tendency toward a higher OS rate in the revised-R0 than revised-R1 group (log-rank p = 0.065), and RFS was significantly better in the revised-R0 than revised-R1 group (log-rank p = 0.002). There was no significant difference in the recurrence patterns between the current-R0 and current-R1 groups. In contrast, the local recurrence rate was significantly lower in the revised-R0 than revised-R1 group (21% vs. 42%, respectively; p = 0.026)."

According to the news reporters, the research concluded: "The revised classification of surgical resection may be more useful than the current UICC classification for prediction of prognosis and local recurrence of IPDC."

For more information on this research see: Clinical impact of margin status on survival and recurrence pattern after curative-intent surgery for pancreatic cancer. Asian Journal of Surgery, 2019;42(1):93-99. Asian Journal of Surgery can be contacted at: Elsevier Singapore Pte Ltd, 3 Killiney Road 08-01, Winsland House 1, Singapore, 239519, Singapore. (Elsevier - www.elsevier.com; Asian Journal of Surgery - www.journals.elsevier.com/asian-journal-of-surgery/)

Our news correspondents report that additional information may be obtained by contacting Y. Uchida, Kitano Hosp, Tazuke Kofukai Med Res Inst, Dept. of Gastroenterol Surg & Oncol, Kita Ku, Osaka 5308480, Japan. Additional authors for this research include T. Yamamoto and H. Terajima (see also Oncology - Pancreatic Cancer).

(Our reports deliver fact-based news of research and discoveries from around the world.)



Copyright 2019, NewsRx LLC

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